Unique ID: LM0125
Study ID: Ip 2021
Pubmed ID: 34624047
Database Version: 5/17/2023
Title: Effects of a group-based lifestyle medicine for depression: A pilot randomized controlled trial
Publication Year: 2021
Journal: PLoS One
Primary study aim: To examine the effects and acceptability of a group-based, integrative lifestyle medicine intervention as a standalone treatment for managing depressive symptoms, a pilot randomized controlled trial (RCT) was conducted in a Chinese adult population in 2018.
Study Design: randomized controlled trial
What lifestyle pillars were studied? Diet/nutrition, Physical activity, Sleep, Stress/mental health, Social connection
For diet/nutrition studies, what was the dietary pattern studied? Other: Chinese diet-based (Guangdong dishes, soups, and herbal tea)
Please select the population(s) studied: adults (18-54 yrs)
What is the mean age of the study population? 35.1
What was the age range of the study population? 18-61
What was the mean BMI of the study population (kg/m2)? NR
What was the BMI range of the study population (kg/m2)? NR
What is the health status of the study population? Other: Depression
Sex (% male): 16.1
Int: Study blindness: not blinded
Int: Study randomization: randomized
Int: Study duration (numeric only): 6
Int: Study duration (select corresponding units): weeks
Int: Sample size: 31
Int: Sample size reported is: Recruited
Int: What was the intervention used in this study (1)?
The intervention protocol was modified and enhanced from the Healthy Body Healthy Mind
(HBHM) integrative lifestyle program was designed to integrate five evidence-based
lifestyle components, including diet, exercise, mindfulness, psychoeducation, and sleep management, alongside motivational and goal-setting skills and lifestyle psychoeducation
Int: What was the comparator(s) used in this study (1)? Care-as-usual
Study outcome 1: Patient Health Questionnaire (PHQ-9)
Outcome group 1: mental health/psychological outcomes
Study outcome 2: Depression/anxiety (DASS-21)
Outcome group 2: mental health/psychological outcomes
Study outcome 3: Insomnia (ISI)
Outcome group 3: Other: sleep
Study outcome 4: Fatigue (MFI-20)
Outcome group 4: patient well-being
Study outcome 5: Quality of life (SF-6D)
Outcome group 5: quality of life
Study outcome 6: Fatigue (MFI)
Outcome group 6: patient well-being
Study outcome 7: Disability (SDS)
Outcome group 7: quality of life
Study outcome 8: Credibility/expectancy (CEQ)
Outcome group 8: quality of life
Key conclusion: They demonstrated that the group-based, integrated LM intervention could be an effective and acceptable treatment option for depressed adults.