Unique ID: LM0118
Study ID: Ding 2023
Pubmed ID: 36806378
Database Version: 5/17/2023
Title: Effectiveness of lifestyle medicine on cognitive functions in mild cognitive impairments and dementia: A systematic review on randomized controlled trials
Author list: Zihan Ding, Pui-Ying Leung, Tsz-Lok Lee, Agnes S Chan
Publication Year: 2023
Journal: Ageing Research Reviews
Primary study aim:

The present study aims to examine the
effectiveness of lifestyle medicine on cognitive functions among people with MCI and dementia, by performing a
systematic review and meta-analysis on randomized controlled trials (RCT).

Study Design: systematic review
What lifestyle pillars were studied? Diet/nutrition, Physical activity, Stress/mental health
Please select the population(s) studied: adults (18-54 yrs)
What is the mean age of the study population? NR
What was the age range of the study population? NR
What was the mean BMI of the study population (kg/m2)? NR
What was the BMI range of the study population (kg/m2)? NR
Sex (% male): NR
SR: What was the primary outcome? Exercise was the most promising lifestyle intervention that improved various cognitive functions among people with MCI and dementia, and was more effective in MCI than in dementia.
SR: What was the total n for the primary outcome? 67
Study outcome 1: Exercise moderators
Outcome group 1: physical activity
Study outcome 2: Cognitive moderators
Outcome group 2: mental health/psychological outcomes
Key conclusion: Exercise component of lifestyle medicine can be an effective and clinically significant intervention for protecting people with MCI and dementia against cognitive declines, especially when served as an early intervention at the stage of MCI.